A citation-based method for searching scientific literature

Owen M Peters, Gabriela Toro Cabrera, Helene Tran, Tania F Gendron, Jeanne E McKeon, Jake Metterville, Alexandra Weiss, Nicholas Wightman, Johnny Salameh, Juyhun Kim, Huaming Sun, Kevin B Boylan, Dennis Dickson, Zack Kennedy, Ziqiang Lin, Yong-Jie Zhang, Lillian Daughrity, Chris Jung, Fen-Biao Gao, Peter C Sapp, H Robert Horvitz, Daryl A Bosco, Solange P Brown, Pieter de Jong, Leonard Petrucelli, Chris Mueller, Robert H Brown. Neuron 2015
Times Cited: 159



Jie Jiang, Qiang Zhu, Tania F Gendron, Shahram Saberi, Melissa McAlonis-Downes, Amanda Seelman, Jennifer E Stauffer, Paymaan Jafar-Nejad, Kevin Drenner, Derek Schulte, Seung Chun, Shuying Sun, Shuo-Chien Ling, Brian Myers, Jeffery Engelhardt, Melanie Katz, Michael Baughn, Oleksandr Platoshyn, Martin Marsala, Andy Watt, Charles J Heyser, M Colin Ard, Louis De Muynck, Lillian M Daughrity, Deborah A Swing, Lino Tessarollo, Chris J Jung, Arnaud Delpoux, Daniel T Utzschneider, Stephen M Hedrick, Pieter J de Jong, Dieter Edbauer, Philip Van Damme, Leonard Petrucelli, Christopher E Shaw, C Frank Bennett, Sandrine Da Cruz, John Ravits, Frank Rigo, Don W Cleveland, Clotilde Lagier-Tourenne. Neuron 2016
Times Cited: 270




List of shared articles



Times cited

Sizing, stabilising, and cloning repeat-expansions for gene targeting constructs.
Remya R Nair, Charlotte Tibbit, David Thompson, Ross McLeod, Asif Nakhuda, Michelle M Simon, Robert H Baloh, Elizabeth M C Fisher, Adrian M Isaacs, Thomas J Cunningham. Methods 2021
1

Ablation of C9orf72 together with excitotoxicity induces ALS in rats.
Wei Dong, Yuanwu Ma, Feifei Guan, Xu Zhang, Wei Chen, Li Zhang, Lianfeng Zhang. FEBS J 2021
2

Long non-coding RNAs in motor neuron development and disease.
Vamshidhar R Vangoor, Andreia Gomes-Duarte, R Jeroen Pasterkamp. J Neurochem 2021
5

Repeat length increases disease penetrance and severity in C9orf72 ALS/FTD BAC transgenic mice.
Amrutha Pattamatta, Lien Nguyen, Hailey R Olafson, Marina M Scotti, Lauren A Laboissonniere, Jared Richardson, J Andrew Berglund, Tao Zu, Eric T Wang, Laura P W Ranum. Hum Mol Genet 2021
1

Inducible expression of human C9ORF72 36x G4C2 hexanucleotide repeats is sufficient to cause RAN translation and rapid muscular atrophy in mice.
F W Riemslagh, E C van der Toorn, R F M Verhagen, A Maas, L W J Bosman, R K Hukema, R Willemsen. Dis Model Mech 2021
2

Glial Cell Dysfunction in C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Mehdi Ghasemi, Kiandokht Keyhanian, Catherine Douthwright. Cells 2021
3

Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models.
Yuanjing Liu, Jean-Cosme Dodart, Helene Tran, Shaunna Berkovitch, Maurine Braun, Michael Byrne, Ann F Durbin, Xiao Shelley Hu, Naoki Iwamoto, Hyun Gyung Jang,[...]. Nat Commun 2021
3

C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
Jimmy Beckers, Arun Kumar Tharkeshwar, Philip Van Damme. Autophagy 2021
2

BET bromodomain inhibitors PFI-1 and JQ1 are identified in an epigenetic compound screen to enhance C9ORF72 gene expression and shown to ameliorate C9ORF72-associated pathological and behavioral abnormalities in a C9ALS/FTD model.
Esteban Quezada, Claudio Cappelli, Iván Diaz, Nur Jury, Nicholas Wightman, Robert H Brown, Martín Montecino, Brigitte van Zundert. Clin Epigenetics 2021
0

Expression of C9orf72 hexanucleotide repeat expansion leads to formation of RNA foci and dipeptide repeat proteins but does not influence autophagy or proteasomal function in neuronal cells.
Stina Leskelä, Nadine Huber, Dorit Hoffmann, Hannah Rostalski, Anne M Remes, Mari Takalo, Mikko Hiltunen, Annakaisa Haapasalo. Biochim Biophys Acta Mol Cell Res 2021
0

Non-neuronal cells in amyotrophic lateral sclerosis - from pathogenesis to biomarkers.
Björn F Vahsen, Elizabeth Gray, Alexander G Thompson, Olaf Ansorge, Daniel C Anthony, Sally A Cowley, Kevin Talbot, Martin R Turner. Nat Rev Neurol 2021
4

C9ORF72: What It Is, What It Does, and Why It Matters.
Julie Smeyers, Elena-Gaia Banchi, Morwena Latouche. Front Cell Neurosci 2021
1

Interplay between immunity and amyotrophic lateral sclerosis: Clinical impact.
Fabiola De Marchi, Ivana Munitic, Amedeo Amedei, James D Berry, Eva L Feldman, Eleonora Aronica, Giovanni Nardo, Donatienne Van Weehaeghe, Elena Niccolai, Nikolina Prtenjaca,[...]. Neurosci Biobehav Rev 2021
0

Stem Cell Models and Gene Targeting for Human Motor Neuron Diseases.
Yashashree Karpe, Zhenyu Chen, Xue-Jun Li. Pharmaceuticals (Basel) 2021
0

NRF2 as a therapeutic opportunity to impact in the molecular roadmap of ALS.
J Jiménez-Villegas, L Ferraiuolo, R J Mead, P J Shaw, A Cuadrado, A I Rojo. Free Radic Biol Med 2021
0

RNA Deregulation in Amyotrophic Lateral Sclerosis: The Noncoding Perspective.
Pietro Laneve, Paolo Tollis, Elisa Caffarelli. Int J Mol Sci 2021
0

Modeling cell-autonomous motor neuron phenotypes in ALS using iPSCs.
James Hawrot, Sophie Imhof, Brian J Wainger. Neurobiol Dis 2020
17

Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model.
Lien Nguyen, Fabio Montrasio, Amrutha Pattamatta, Solaleh Khoramian Tusi, Olgert Bardhi, Kevin D Meyer, Lindsey Hayes, Katsuya Nakamura, Monica Banez-Coronel, Alyssa Coyne,[...]. Neuron 2020
22

Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders.
Manon Boivin, Véronique Pfister, Angeline Gaucherot, Frank Ruffenach, Luc Negroni, Chantal Sellier, Nicolas Charlet-Berguerand. EMBO J 2020
33

Glial Cells-The Strategic Targets in Amyotrophic Lateral Sclerosis Treatment.
Tereza Filipi, Zuzana Hermanova, Jana Tureckova, Ondrej Vanatko, And Miroslava Anderova. J Clin Med 2020
15

Widespread loss of the silencing epigenetic mark H3K9me3 in astrocytes and neurons along with hippocampal-dependent cognitive impairment in C9orf72 BAC transgenic mice.
Nur Jury, Sebastian Abarzua, Ivan Diaz, Miguel V Guerra, Estibaliz Ampuero, Paula Cubillos, Pablo Martinez, Andrea Herrera-Soto, Cristian Arredondo, Fabiola Rojas,[...]. Clin Epigenetics 2020
8


The Overlapping Genetics of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Yevgeniya A Abramzon, Pietro Fratta, Bryan J Traynor, Ruth Chia. Front Neurosci 2020
37

Omics Approach to Axonal Dysfunction of Motor Neurons in Amyotrophic Lateral Sclerosis (ALS).
Naoki Suzuki, Tetsuya Akiyama, Hitoshi Warita, Masashi Aoki. Front Neurosci 2020
9

Metabolomics: A Tool to Understand the Impact of Genetic Mutations in Amyotrophic Lateral Sclerosis.
Débora Lanznaster, Charlotte Veyrat-Durebex, Patrick Vourc'h, Christian R Andres, Hélène Blasco, Philippe Corcia. Genes (Basel) 2020
3

Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD.
Xiaoqiang Tang, Arturo Toro, Sahana T G, Junli Gao, Jessica Chalk, Björn Oskarsson, Ke Zhang. Mol Neurodegener 2020
9

Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
Katherine D LaClair, Qihui Zhou, Meike Michaelsen, Benedikt Wefers, Monika S Brill, Aleksandar Janjic, Birgit Rathkolb, Daniel Farny, Mikolaj Cygan, Martin Hrabe de Angelis,[...]. Acta Neuropathol 2020
6

RNA-mediated toxicity in C9orf72 ALS and FTD.
Zachary T McEachin, Janani Parameswaran, Nisha Raj, Gary J Bassell, Jie Jiang. Neurobiol Dis 2020
4

Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Zongbing Hao, Rui Wang, Haigang Ren, Guanghui Wang. Neurosci Bull 2020
1

Insights into disease mechanisms and potential therapeutics for C9orf72-related amyotrophic lateral sclerosis/frontotemporal dementia.
Delia Gagliardi, Gianluca Costamagna, Michela Taiana, Luca Andreoli, Fabio Biella, Margherita Bersani, Nereo Bresolin, Giacomo Pietro Comi, Stefania Corti. Ageing Res Rev 2020
1


Preclinical models of disease and multimorbidity with focus upon cardiovascular disease and dementia.
Osman Shabir, Tobias A Moll, Martyna M Matuszyk, Beth Eyre, Manmohi D Dake, Jason Berwick, Sheila E Francis. Mech Ageing Dev 2020
2

Survival and Motor Phenotypes in FVB C9-500 ALS/FTD BAC Transgenic Mice Reproduced by Multiple Labs.
Lien Nguyen, Lauren A Laboissonniere, Shu Guo, Federica Pilotto, Olivier Scheidegger, Angelina Oestmann, Jennetta W Hammond, Herman Li, Anu Hyysalo, Roosa Peltola,[...]. Neuron 2020
3

Absence of Survival and Motor Deficits in 500 Repeat C9ORF72 BAC Mice.
Daniel A Mordes, Brett M Morrison, Xanthe H Ament, Christopher Cantrell, Joanie Mok, Pierce Eggan, Carolyn Xue, Jin-Yuan Wang, Kevin Eggan, Jeffrey D Rothstein. Neuron 2020
7

Knock in of a hexanucleotide repeat expansion in the C9orf72 gene induces ALS in rats.
Wei Dong, Li Zhang, Caixian Sun, Xiang Gao, Feifei Guan, Jing Li, Wei Chen, Yuanwu Ma, Lianfeng Zhang. Animal Model Exp Med 2020
5

Gene Therapy for Neurodegenerative Diseases: Slowing Down the Ticking Clock.
Raygene Martier, Pavlina Konstantinova. Front Neurosci 2020
6



RNA Binding Proteins and the Pathogenesis of Frontotemporal Lobar Degeneration.
Jeffrey W Hofmann, William W Seeley, Eric J Huang. Annu Rev Pathol 2019
11

Review: Modelling the pathology and behaviour of frontotemporal dementia.
D A Solomon, J C Mitchell, M-T Salcher-Konrad, C A Vance, S Mizielinska. Neuropathol Appl Neurobiol 2019
7

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy.
Jeannie Chew, Casey Cook, Tania F Gendron, Karen Jansen-West, Giulia Del Rosso, Lillian M Daughrity, Monica Castanedes-Casey, Aishe Kurti, Jeannette N Stankowski, Matthew D Disney,[...]. Mol Neurodegener 2019
42

Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion.
Mirjana Babić Leko, Vera Župunski, Jason Kirincich, Dinko Smilović, Tibor Hortobágyi, Patrick R Hof, Goran Šimić. Behav Neurol 2019
25

Artificial MicroRNAs Targeting C9orf72 Can Reduce Accumulation of Intra-nuclear Transcripts in ALS and FTD Patients.
Raygene Martier, Jolanda M Liefhebber, Jana Miniarikova, Tom van der Zon, Jolanda Snapper, Iris Kolder, Harald Petry, Sander J van Deventer, Melvin M Evers, Pavlina Konstantinova. Mol Ther Nucleic Acids 2019
20

Targeting RNA-Mediated Toxicity in C9orf72 ALS and/or FTD by RNAi-Based Gene Therapy.
Raygene Martier, Jolanda M Liefhebber, Ana García-Osta, Jana Miniarikova, Mar Cuadrado-Tejedor, Maria Espelosin, Susana Ursua, Harald Petry, Sander J van Deventer, Melvin M Evers,[...]. Mol Ther Nucleic Acids 2019
37

C9orf72 deficiency promotes motor deficits of a C9ALS/FTD mouse model in a dose-dependent manner.
Qiang Shao, Chen Liang, Qing Chang, Wei Zhang, Mei Yang, Jian-Fu Chen. Acta Neuropathol Commun 2019
25

Repeat-associated non-AUG (RAN) translation: insights from pathology.
Monica Banez-Coronel, Laura P W Ranum. Lab Invest 2019
14

Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS.
Hannah Rostalski, Stina Leskelä, Nadine Huber, Kasper Katisko, Antti Cajanus, Eino Solje, Mikael Marttinen, Teemu Natunen, Anne M Remes, Mikko Hiltunen,[...]. Front Neurosci 2019
19

Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR.
Zongbing Hao, Liu Liu, Zhouteng Tao, Rui Wang, Haigang Ren, Hongyang Sun, Zixuan Lin, Zhixiong Zhang, Chenchen Mu, Jiawei Zhou,[...]. Nat Commun 2019
26

Gene Therapy for ALS-A Perspective.
Marisa Cappella, Chiara Ciotti, Mathilde Cohen-Tannoudji, Maria Grazia Biferi. Int J Mol Sci 2019
35

Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models.
Chen Liang, Qiang Shao, Wei Zhang, Mei Yang, Qing Chang, Rong Chen, Jian-Fu Chen. Hum Mol Genet 2019
8