A citation-based method for searching scientific literature

Yong-Jie Zhang, Tania F Gendron, Mark T W Ebbert, Aliesha D O'Raw, Mei Yue, Karen Jansen-West, Xu Zhang, Mercedes Prudencio, Jeannie Chew, Casey N Cook, Lillian M Daughrity, Jimei Tong, Yuping Song, Sarah R Pickles, Monica Castanedes-Casey, Aishe Kurti, Rosa Rademakers, Bjorn Oskarsson, Dennis W Dickson, Wenqian Hu, Aaron D Gitler, John D Fryer, Leonard Petrucelli. Nat Med 2018
Times Cited: 144



Tania F Gendron, Kevin F Bieniek, Yong-Jie Zhang, Karen Jansen-West, Peter E A Ash, Thomas Caulfield, Lillian Daughrity, Judith H Dunmore, Monica Castanedes-Casey, Jeannie Chew, Danielle M Cosio, Marka van Blitterswijk, Wing C Lee, Rosa Rademakers, Kevin B Boylan, Dennis W Dickson, Leonard Petrucelli. Acta Neuropathol 2013
Times Cited: 372




List of shared articles



Times cited

C9orf72 ALS/FTD dipeptide repeat protein levels are reduced by small molecules that inhibit PKA or enhance protein degradation.
Nausicaa V Licata, Riccardo Cristofani, Sally Salomonsson, Katherine M Wilson, Liam Kempthorne, Deniz Vaizoglu, Vito G D'Agostino, Daniele Pollini, Rosa Loffredo, Michael Pancher,[...]. EMBO J 2022
1

The molecular pathogenesis of repeat expansion diseases.
Yuzo Fujino, Yoshitaka Nagai. Biochem Soc Trans 2022
0

Partners in crime: Proteins implicated in RNA repeat expansion diseases.
Anna Baud, Magdalena Derbis, Katarzyna Tutak, Krzysztof Sobczak. Wiley Interdiscip Rev RNA 2022
0

Modelling amyotrophic lateral sclerosis in rodents.
Tiffany W Todd, Leonard Petrucelli. Nat Rev Neurosci 2022
1

Dual-gRNA approach with limited off-target effect corrects C9ORF72 repeat expansion in vivo.
Xuejiao Piao, Dawei Meng, Xue Zhang, Qiang Song, Hailong Lv, Yichang Jia. Sci Rep 2022
0

Antisense Oligonucleotides for the Study and Treatment of ALS.
Benjamin D Boros, Kathleen M Schoch, Collin J Kreple, Timothy M Miller. Neurotherapeutics 2022
0

NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility.
Amanda M Gleixner, Brandie Morris Verdone, Charlton G Otte, Eric N Anderson, Nandini Ramesh, Olivia R Shapiro, Jenna R Gale, Jocelyn C Mauna, Jacob R Mann, Katie E Copley,[...]. Nat Commun 2022
0


Inducible expression of human C9ORF72 36x G4C2 hexanucleotide repeats is sufficient to cause RAN translation and rapid muscular atrophy in mice.
F W Riemslagh, E C van der Toorn, R F M Verhagen, A Maas, L W J Bosman, R K Hukema, R Willemsen. Dis Model Mech 2021
4

Glial Cell Dysfunction in C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Mehdi Ghasemi, Kiandokht Keyhanian, Catherine Douthwright. Cells 2021
5

Emerging Perspectives on Dipeptide Repeat Proteins in C9ORF72 ALS/FTD.
Alexander Schmitz, João Pinheiro Marques, Irina Oertig, Niran Maharjan, Smita Saxena. Front Cell Neurosci 2021
10

Mechanisms of repeat-associated non-AUG translation in neurological microsatellite expansion disorders.
Lydia M Castelli, Wan-Ping Huang, Ya-Hui Lin, Kung-Yao Chang, Guillaume M Hautbergue. Biochem Soc Trans 2021
5

Proteostatic imbalance and protein spreading in amyotrophic lateral sclerosis.
Maria Elena Cicardi, Lara Marrone, Mimoun Azzouz, Davide Trotti. EMBO J 2021
8

Hypothesis and Theory: Roles of Arginine Methylation in C9orf72-Mediated ALS and FTD.
Anna L Gill, Alan S Premasiri, Fernando G Vieira. Front Cell Neurosci 2021
1

Altered Phase Separation and Cellular Impact in C9orf72-Linked ALS/FTD.
Daniel A Solomon, Rebekah Smikle, Matthew J Reid, Sarah Mizielinska. Front Cell Neurosci 2021
6

Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis.
Maria Babu, Filippo Favretto, Alain Ibáñez de Opakua, Marija Rankovic, Stefan Becker, Markus Zweckstetter. Nat Commun 2021
1

Molecular mechanisms underlying nucleotide repeat expansion disorders.
Indranil Malik, Chase P Kelley, Eric T Wang, Peter K Todd. Nat Rev Mol Cell Biol 2021
19

Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model.
Frédéric Frottin, Manuela Pérez-Berlanga, F Ulrich Hartl, Mark S Hipp. Elife 2021
4

RNA Is a Double-Edged Sword in ALS Pathogenesis.
Benjamin L Zaepfel, Jeffrey D Rothstein. Front Cell Neurosci 2021
2

The Skeletal Muscle Emerges as a New Disease Target in Amyotrophic Lateral Sclerosis.
Oihane Pikatza-Menoio, Amaia Elicegui, Xabier Bengoetxea, Neia Naldaiz-Gastesi, Adolfo López de Munain, Gorka Gerenu, Francisco Javier Gil-Bea, Sonia Alonso-Martín. J Pers Med 2021
6

Therapeutic strategies for C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia.
Guillaume M Hautbergue, John D Cleary, Shu Guo, Laura P W Ranum. Curr Opin Neurol 2021
3

Elucidating the Role of Cerebellar Synaptic Dysfunction in C9orf72-ALS/FTD - a Systematic Review and Meta-Analysis.
Aleksandra Kaliszewska, Joseph Allison, Tarik-Tarkan Col, Christopher Shaw, Natalia Arias. Cerebellum 2021
0

SRSF protein kinase 1 modulates RAN translation and suppresses CGG repeat toxicity.
Indranil Malik, Yi-Ju Tseng, Shannon E Wright, Kristina Zheng, Prithika Ramaiyer, Katelyn M Green, Peter K Todd. EMBO Mol Med 2021
5

Reduction of oxidative stress suppresses poly-GR-mediated toxicity in zebrafish embryos.
Fréderike W Riemslagh, Rob F M Verhagen, Esmay C van der Toorn, Daphne J Smits, Wim H Quint, Herma C van der Linde, Tjakko J van Ham, Rob Willemsen. Dis Model Mech 2021
0

p53 Transactivation Domain Mediates Binding and Phase Separation with Poly-PR/GR.
Sinem Usluer, Emil Spreitzer, Benjamin Bourgeois, Tobias Madl. Int J Mol Sci 2021
0

Epigenetic Small Molecules Rescue Nucleocytoplasmic Transport and DNA Damage Phenotypes in C9ORF72 ALS/FTD.
Melina Ramic, Nadja S Andrade, Matthew J Rybin, Rustam Esanov, Claes Wahlestedt, Michael Benatar, Zane Zeier. Brain Sci 2021
1

Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders.
Manon Boivin, Véronique Pfister, Angeline Gaucherot, Frank Ruffenach, Luc Negroni, Chantal Sellier, Nicolas Charlet-Berguerand. EMBO J 2020
47

Arginine in C9ORF72 Dipolypeptides Mediates Promiscuous Proteome Binding and Multiple Modes of Toxicity.
Mona Radwan, Ching-Seng Ang, Angelique R Ormsby, Dezerae Cox, James C Daly, Gavin E Reid, Danny M Hatters. Mol Cell Proteomics 2020
13

C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import.
Lindsey R Hayes, Lauren Duan, Kelly Bowen, Petr Kalab, Jeffrey D Rothstein. Elife 2020
48

Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo.
Tiffany W Todd, Zachary T McEachin, Jeannie Chew, Alexander R Burch, Karen Jansen-West, Jimei Tong, Mei Yue, Yuping Song, Monica Castanedes-Casey, Aishe Kurti,[...]. Cell Rep 2020
14

Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36.
Zachary T McEachin, Tania F Gendron, Nisha Raj, María García-Murias, Anwesha Banerjee, Ryan H Purcell, Patricia J Ward, Tiffany W Todd, Megan E Merritt-Garza, Karen Jansen-West,[...]. Neuron 2020
23

Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD.
Xiaoqiang Tang, Arturo Toro, Sahana T G, Junli Gao, Jessica Chalk, Björn Oskarsson, Ke Zhang. Mol Neurodegener 2020
10

Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD.
Hana M Odeh, James Shorter. Emerg Top Life Sci 2020
13

Phase Separation of Toxic Dipeptide Repeat Proteins Related to C9orf72 ALS/FTD.
Hamidreza Jafarinia, Erik van der Giessen, Patrick R Onck. Biophys J 2020
5

The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD.
Fang He, Brittany N Flores, Amy Krans, Michelle Frazer, Sam Natla, Sarjina Niraula, Olamide Adefioye, Sami J Barmada, Peter K Todd. Acta Neuropathol Commun 2020
5

RNA-mediated toxicity in C9orf72 ALS and FTD.
Zachary T McEachin, Janani Parameswaran, Nisha Raj, Gary J Bassell, Jie Jiang. Neurobiol Dis 2020
11

The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS.
Yuya Kawabe, Kohji Mori, Tomoko Yamashita, Shiho Gotoh, Manabu Ikeda. EMBO J 2020
7


Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Zongbing Hao, Rui Wang, Haigang Ren, Guanghui Wang. Neurosci Bull 2020
2

C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy.
Casey N Cook, Yanwei Wu, Hana M Odeh, Tania F Gendron, Karen Jansen-West, Giulia Del Rosso, Mei Yue, Peizhou Jiang, Edward Gomes, Jimei Tong,[...]. Sci Transl Med 2020
49

ALS Genetics: Gains, Losses, and Implications for Future Therapies.
Garam Kim, Olivia Gautier, Eduardo Tassoni-Tsuchida, X Rosa Ma, Aaron D Gitler. Neuron 2020
77


Modelling C9orf72-Related Amyotrophic Lateral Sclerosis in Zebrafish.
Gabrielle Fortier, Zoé Butti, Shunmoogum A Patten. Biomedicines 2020
5


Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions.
Saskia Hutten, Sinem Usluer, Benjamin Bourgeois, Francesca Simonetti, Hana M Odeh, Charlotte M Fare, Mareike Czuppa, Marian Hruska-Plochan, Mario Hofweber, Magdalini Polymenidou,[...]. Cell Rep 2020
24