A citation-based method for searching scientific literature

Marc Ciosi, Alastair Maxwell, Sarah A Cumming, Davina J Hensman Moss, Asma M Alshammari, Michael D Flower, Alexandra Durr, Blair R Leavitt, Raymund A C Roos, Peter Holmans, Lesley Jones, Douglas R Langbehn, Seung Kwak, Sarah J Tabrizi, Darren G Monckton. EBioMedicine 2019
Times Cited: 58







List of shared articles



Times cited

DNA methylation study of Huntington's disease and motor progression in patients and in animal models.
Ake T Lu, Pritika Narayan, Matthew J Grant, Peter Langfelder, Nan Wang, Seung Kwak, Hilary Wilkinson, Richard Z Chen, Jian Chen, C Simon Bawden,[...]. Nat Commun 2020
12

Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
Jacob M Loupe, Ricardo Mouro Pinto, Kyung-Hee Kim, Tammy Gillis, Jayalakshmi S Mysore, Marissa A Andrew, Marina Kovalenko, Ryan Murtha, IhnSik Seong, James F Gusella,[...]. Hum Mol Genet 2020
22

Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice.
Xiaofeng Gu, Jeffrey Richman, Peter Langfelder, Nan Wang, Shasha Zhang, Monica Bañez-Coronel, Huei-Bin Wang, Lucia Yang, Lalini Ramanathan, Linna Deng,[...]. Neuron 2022
2

DNA Repair in Huntington's Disease and Spinocerebellar Ataxias: Somatic Instability and Alternative Hypotheses.
Tamara Maiuri, Claudia L K Hung, Celeste Suart, Nola Begeja, Carlos Barba-Bazan, Yi Peng, Natasha Savic, Timothy Wong, Ray Truant. J Huntingtons Dis 2021
11

HDAC3 deacetylates the DNA mismatch repair factor MutSβ to stimulate triplet repeat expansions.
Gregory M Williams, Vasileios Paschalis, Janice Ortega, Frederick W Muskett, James T Hodgkinson, Guo-Min Li, John W R Schwabe, Robert S Lahue. Proc Natl Acad Sci U S A 2020
9

Modifiers of Somatic Repeat Instability in Mouse Models of Friedreich Ataxia and the Fragile X-Related Disorders: Implications for the Mechanism of Somatic Expansion in Huntington's Disease.
Xiaonan Zhao, Daman Kumari, Carson J Miller, Geum-Yi Kim, Bruce Hayward, Antonia G Vitalo, Ricardo Mouro Pinto, Karen Usdin. J Huntingtons Dis 2021
10


FAN1 exo- not endo-nuclease pausing on disease-associated slipped-DNA repeats: A mechanism of repeat instability.
Amit Laxmikant Deshmukh, Marie-Christine Caron, Mohiuddin Mohiuddin, Stella Lanni, Gagan B Panigrahi, Mahreen Khan, Worrawat Engchuan, Natalie Shum, Aisha Faruqui, Peixiang Wang,[...]. Cell Rep 2021
1

Tracing the mutated HTT and haplotype of the African ancestor who spread Huntington disease into the Middle East.
Ferdinando Squitieri, Tommaso Mazza, Sabrina Maffi, Alessandro De Luca, Qasem AlSalmi, Salma AlHarasi, Jennifer A Collins, Chris Kay, Fiona Baine-Savanhu, Bernard G Landwhermeyer,[...]. Genet Med 2020
3

Mutations causing Lopes-Maciel-Rodan syndrome are huntingtin hypomorphs.
Roy Jung, Yejin Lee, Douglas Barker, Kevin Correia, Baehyun Shin, Jacob Loupe, Ryan L Collins, Diane Lucente, Jayla Ruliera, Tammy Gillis,[...]. Hum Mol Genet 2021
2

Replication-independent instability of Friedreich's ataxia GAA repeats during chronological aging.
Alexander J Neil, Julia A Hisey, Ishtiaque Quasem, Ryan J McGinty, Marcin Hitczenko, Alexandra N Khristich, Sergei M Mirkin. Proc Natl Acad Sci U S A 2021
4

Association Analysis of Chromosome X to Identify Genetic Modifiers of Huntington's Disease.
Eun Pyo Hong, Michael J Chao, Thomas Massey, Branduff McAllister, Sergey Lobanov, Lesley Jones, Peter Holmans, Seung Kwak, Michael Orth, Marc Ciosi,[...]. J Huntingtons Dis 2021
1

Targeting Expanded Repeats by Small Molecules in Repeat Expansion Disorders.
Masayuki Nakamori, Hideki Mochizuki. Mov Disord 2021
3


Drugging DNA Damage Repair Pathways for Trinucleotide Repeat Expansion Diseases.
Caroline L Benn, Karl R Gibson, David S Reynolds. J Huntingtons Dis 2021
10

Structure-forming repeats and their impact on genome stability.
Rebecca E Brown, Catherine H Freudenreich. Curr Opin Genet Dev 2021
7


Interrupting sequence variants and age of onset in Huntington's disease: clinical implications and emerging therapies.
Galen E B Wright, Hailey Findlay Black, Jennifer A Collins, Terence Gall-Duncan, Nicholas S Caron, Christopher E Pearson, Michael R Hayden. Lancet Neurol 2020
17

Genetic and Functional Analyses Point to FAN1 as the Source of Multiple Huntington Disease Modifier Effects.
Kyung-Hee Kim, Eun Pyo Hong, Jun Wan Shin, Michael J Chao, Jacob Loupe, Tammy Gillis, Jayalakshmi S Mysore, Peter Holmans, Lesley Jones, Michael Orth,[...]. Am J Hum Genet 2020
23

Longitudinal increases in somatic mosaicism of the expanded CTG repeat in myotonic dystrophy type 1 are associated with variation in age-at-onset.
Fernando Morales, Melissa Vásquez, Eyleen Corrales, Rebeca Vindas-Smith, Carolina Santamaría-Ulloa, Baili Zhang, Mario Sirito, Marcos R Estecio, Ralf Krahe, Darren G Monckton. Hum Mol Genet 2020
15

Somatic CAG expansion in Huntington's disease is dependent on the MLH3 endonuclease domain, which can be excluded via splice redirection.
Jennie C L Roy, Antonia Vitalo, Marissa A Andrew, Eduarda Mota-Silva, Marina Kovalenko, Zoe Burch, Anh M Nhu, Paula E Cohen, Ed Grabczyk, Vanessa C Wheeler,[...]. Nucleic Acids Res 2021
2

Polyglutamine diseases.
Emma L Bunting, Joseph Hamilton, Sarah J Tabrizi. Curr Opin Neurobiol 2022
3

CAG repeat-binding small molecule improves motor coordination impairment in a mouse model of Dentatorubral-pallidoluysian atrophy.
Yuhei Hasuike, Hana Tanaka, Terence Gall-Duncan, Mustafa Mehkary, Kazuhiko Nakatani, Christopher E Pearson, Shoji Tsuji, Hideki Mochizuki, Masayuki Nakamori. Neurobiol Dis 2022
0

Tissue-specific and repeat length-dependent somatic instability of the X-linked dystonia parkinsonism-associated CCCTCT repeat.
Lindsey N Campion, Alan Mejia Maza, Rachita Yadav, Ellen B Penney, Micaela G Murcar, Kevin Correia, Tammy Gillis, Cara Fernandez-Cerado, M Salvie Velasco-Andrada, G Paul Legarda,[...]. Acta Neuropathol Commun 2022
1

Subcellular Localization And Formation Of Huntingtin Aggregates Correlates With Symptom Onset And Progression In A Huntington'S Disease Model.
Christian Landles, Rebecca E Milton, Nadira Ali, Rachel Flomen, Michael Flower, Franziska Schindler, Casandra Gomez-Paredes, Marie K Bondulich, Georgina F Osborne, Daniel Goodwin,[...]. Brain Commun 2020
16

Huntington's disease: nearly four decades of human molecular genetics.
James F Gusella, Jong-Min Lee, Marcy E MacDonald. Hum Mol Genet 2021
3

Advancing genomic technologies and clinical awareness accelerates discovery of disease-associated tandem repeat sequences.
Terence Gall-Duncan, Nozomu Sato, Ryan K C Yuen, Christopher E Pearson. Genome Res 2022
1

A Glimpse of Molecular Biomarkers in Huntington's Disease.
Silvia Martí-Martínez, Luis M Valor. Int J Mol Sci 2022
0

A small molecule kicks repeat expansion into reverse.
Michael D Flower, Sarah J Tabrizi. Nat Genet 2020
1

Approaches to Sequence the HTT CAG Repeat Expansion and Quantify Repeat Length Variation.
Marc Ciosi, Sarah A Cumming, Afroditi Chatzi, Eloise Larson, William Tottey, Vilija Lomeikaite, Graham Hamilton, Vanessa C Wheeler, Ricardo Mouro Pinto, Seung Kwak,[...]. J Huntingtons Dis 2021
5

Human MutLγ, the MLH1-MLH3 heterodimer, is an endonuclease that promotes DNA expansion.
Lyudmila Y Kadyrova, Vaibhavi Gujar, Vickers Burdett, Paul L Modrich, Farid A Kadyrov. Proc Natl Acad Sci U S A 2020
26




Genetic modifiers of Huntington disease differentially influence motor and cognitive domains.
Jong-Min Lee, Yuan Huang, Michael Orth, Tammy Gillis, Jacqueline Siciliano, Eunpyo Hong, Jayalakshmi Srinidhi Mysore, Diane Lucente, Vanessa C Wheeler, Ihn Sik Seong,[...]. Am J Hum Genet 2022
1

Timing and Impact of Psychiatric, Cognitive, and Motor Abnormalities in Huntington Disease.
Branduff McAllister, James F Gusella, G Bernhard Landwehrmeyer, Jong-Min Lee, Marcy E MacDonald, Michael Orth, Anne E Rosser, Nigel M Williams, Peter Holmans, Lesley Jones,[...]. Neurology 2021
10

Propensity for somatic expansion increases over the course of life in Huntington disease.
Radhia Kacher, François-Xavier Lejeune, Sandrine Noël, Cécile Cazeneuve, Alexis Brice, Sandrine Humbert, Alexandra Durr. Elife 2021
9

Identifying genetic modifiers of age-associated penetrance in X-linked dystonia-parkinsonism.
Björn-Hergen Laabs, Christine Klein, Jelena Pozojevic, Aloysius Domingo, Norbert Brüggemann, Karen Grütz, Raymond L Rosales, Roland Dominic Jamora, Gerard Saranza, Cid Czarina E Diesta,[...]. Nat Commun 2021
6

Stool is a sensitive and noninvasive source of DNA for monitoring expansion in repeat expansion disease mouse models.
Xiaonan Zhao, Cassandra McHugh, Sydney R Coffey, Diego Antonio Jimenez, Elizabeth Adams, Jeffrey B Carroll, Karen Usdin. Dis Model Mech 2022
0

Patterns of CAG repeat instability in the central nervous system and periphery in Huntington's disease and in spinocerebellar ataxia type 1.
Ricardo Mouro Pinto, Larissa Arning, James V Giordano, Pedram Razghandi, Marissa A Andrew, Tammy Gillis, Kevin Correia, Jayalakshmi S Mysore, Debora-M Grote Urtubey, Constanze R Parwez,[...]. Hum Mol Genet 2020
27

TCF4-mediated Fuchs endothelial corneal dystrophy: Insights into a common trinucleotide repeat-associated disease.
Michael P Fautsch, Eric D Wieben, Keith H Baratz, Nihar Bhattacharyya, Amanda N Sadan, Nathaniel J Hafford-Tear, Stephen J Tuft, Alice E Davidson. Prog Retin Eye Res 2021
8

What is the Pathogenic CAG Expansion Length in Huntington's Disease?
Jasmine Donaldson, Sophie Powell, Nadia Rickards, Peter Holmans, Lesley Jones. J Huntingtons Dis 2021
8



Huntington's Disease Pathogenesis: Two Sequential Components.
Eun Pyo Hong, Marcy E MacDonald, Vanessa C Wheeler, Lesley Jones, Peter Holmans, Michael Orth, Darren G Monckton, Jeffrey D Long, Seung Kwak, James F Gusella,[...]. J Huntingtons Dis 2021
16

Modifiers of CAG/CTG Repeat Instability: Insights from Mammalian Models.
Vanessa C Wheeler, Vincent Dion. J Huntingtons Dis 2021
19

Exome sequencing of individuals with Huntington's disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset.
Branduff McAllister, Jasmine Donaldson, Caroline S Binda, Sophie Powell, Uroosa Chughtai, Gareth Edwards, Joseph Stone, Sergey Lobanov, Linda Elliston, Laura-Nadine Schuhmacher,[...]. Nat Neurosci 2022
2

DNA Mismatch Repair and its Role in Huntington's Disease.
Ravi R Iyer, Anna Pluciennik. J Huntingtons Dis 2021
13

FAN1, a DNA Repair Nuclease, as a Modifier of Repeat Expansion Disorders.
Amit L Deshmukh, Antonio Porro, Mohiuddin Mohiuddin, Stella Lanni, Gagan B Panigrahi, Marie-Christine Caron, Jean-Yves Masson, Alessandro A Sartori, Christopher E Pearson. J Huntingtons Dis 2021
10

On the wrong DNA track: Molecular mechanisms of repeat-mediated genome instability.
Alexandra N Khristich, Sergei M Mirkin. J Biol Chem 2020
64