A citation-based method for searching scientific literature

Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72.
Qiang Zhu, Jie Jiang, Tania F Gendron, Melissa McAlonis-Downes, Lulin Jiang, Amy Taylor, Sandra Diaz Garcia, Somasish Ghosh Dastidar, Maria J Rodriguez, Patrick King, Yongjie Zhang, Albert R La Spada, Huaxi Xu, Leonard Petrucelli, John Ravits, Sandrine Da Cruz, Clotilde Lagier-Tourenne, Don W Cleveland. Nat Neurosci 2020
Times Cited: 74



RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia.
Tao Zu, Yuanjing Liu, Monica Bañez-Coronel, Tammy Reid, Olga Pletnikova, Jada Lewis, Timothy M Miller, Matthew B Harms, Annet E Falchook, S H Subramony, Lyle W Ostrow, Jeffrey D Rothstein, Juan C Troncoso, Laura P W Ranum. Proc Natl Acad Sci U S A 2013
Times Cited: 508




List of shared articles



Times cited

Reduced C9orf72 function leads to defective synaptic vesicle release and neuromuscular dysfunction in zebrafish.
Zoé Butti, Yingzhou Edward Pan, Jean Giacomotto, Shunmoogum A Patten. Commun Biol 2021
4

Frontotemporal Dementia and Glucose Metabolism.
Liam Rodney Garrett, Teresa Niccoli. Front Neurosci 2022
0

Emerging Perspectives on Dipeptide Repeat Proteins in C9ORF72 ALS/FTD.
Alexander Schmitz, João Pinheiro Marques, Irina Oertig, Niran Maharjan, Smita Saxena. Front Cell Neurosci 2021
10

Modelling amyotrophic lateral sclerosis in rodents.
Tiffany W Todd, Leonard Petrucelli. Nat Rev Neurosci 2022
1

Preclinical evaluation of WVE-004, aninvestigational stereopure oligonucleotide forthe treatment of C9orf72-associated ALS or FTD.
Yuanjing Liu, Amy Andreucci, Naoki Iwamoto, Yuan Yin, Hailin Yang, Fangjun Liu, Alexey Bulychev, Xiao Shelley Hu, Xuena Lin, Sarah Lamore,[...]. Mol Ther Nucleic Acids 2022
1

RNA-mediated toxicity in C9orf72 ALS and FTD.
Zachary T McEachin, Janani Parameswaran, Nisha Raj, Gary J Bassell, Jie Jiang. Neurobiol Dis 2020
11

Divergence, Convergence, and Therapeutic Implications: A Cell Biology Perspective of C9ORF72-ALS/FTD.
Xiaoqiang Tang, Arturo Toro, Sahana T G, Junli Gao, Jessica Chalk, Björn Oskarsson, Ke Zhang. Mol Neurodegener 2020
10

Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide.
Hélène Tran, Michael P Moazami, Huiya Yang, Diane McKenna-Yasek, Catherine L Douthwright, Courtney Pinto, Jake Metterville, Minwook Shin, Nitasha Sanil, Craig Dooley,[...]. Nat Med 2022
2

Molecular mechanisms underlying nucleotide repeat expansion disorders.
Indranil Malik, Chase P Kelley, Eric T Wang, Peter K Todd. Nat Rev Mol Cell Biol 2021
19

Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models.
Yuanjing Liu, Jean-Cosme Dodart, Helene Tran, Shaunna Berkovitch, Maurine Braun, Michael Byrne, Ann F Durbin, Xiao Shelley Hu, Naoki Iwamoto, Hyun Gyung Jang,[...]. Nat Commun 2021
17

The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene.
Kohji Mori, Shiho Gotoh, Tomoko Yamashita, Ryota Uozumi, Yuya Kawabe, Shinji Tagami, Frits Kamp, Brigitte Nuscher, Dieter Edbauer, Christian Haass,[...]. J Biol Chem 2021
2

Proteostasis deregulation as a driver of C9ORF72 pathogenesis.
Paulina Torres, Felipe Cabral-Miranda, Vicente Gonzalez-Teuber, Claudio Hetz. J Neurochem 2021
1

Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD.
Hana M Odeh, James Shorter. Emerg Top Life Sci 2020
13

Modelling C9orf72-Related Amyotrophic Lateral Sclerosis in Zebrafish.
Gabrielle Fortier, Zoé Butti, Shunmoogum A Patten. Biomedicines 2020
5

Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model.
Frédéric Frottin, Manuela Pérez-Berlanga, F Ulrich Hartl, Mark S Hipp. Elife 2021
4

C9ORF72: What It Is, What It Does, and Why It Matters.
Julie Smeyers, Elena-Gaia Banchi, Morwena Latouche. Front Cell Neurosci 2021
10

A mouse model with widespread expression of the C9orf72-linked glycine-arginine dipeptide displays non-lethal ALS/FTD-like phenotypes.
Brandie Morris Verdone, Maria Elena Cicardi, Xinmei Wen, Sindhu Sriramoji, Katelyn Russell, Shashirekha S Markandaiah, Brigid K Jensen, Karthik Krishnamurthy, Aaron R Haeusler, Piera Pasinelli,[...]. Sci Rep 2022
1

ALS Genetics: Gains, Losses, and Implications for Future Therapies.
Garam Kim, Olivia Gautier, Eduardo Tassoni-Tsuchida, X Rosa Ma, Aaron D Gitler. Neuron 2020
77

Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia.
Ramya Ranganathan, Shaila Haque, Kayesha Coley, Stephanie Shepheard, Johnathan Cooper-Knock, Janine Kirby. Front Neurosci 2020
9

The Development of C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Disorders.
Qijie Yang, Bin Jiao, Lu Shen. Front Genet 2020
7

The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS.
Yuya Kawabe, Kohji Mori, Tomoko Yamashita, Shiho Gotoh, Manabu Ikeda. EMBO J 2020
7

RNA dependent suppression of C9orf72 ALS/FTD associated neurodegeneration by Matrin-3.
Nandini Ramesh, Elizabeth L Daley, Amanda M Gleixner, Jacob R Mann, Sukhleen Kour, Darilang Mawrie, Eric N Anderson, Julia Kofler, Christopher J Donnelly, Evangelos Kiskinis,[...]. Acta Neuropathol Commun 2020
10

Cellular and physiological functions of C9ORF72 and implications for ALS/FTD.
Weilun Pang, Fenghua Hu. J Neurochem 2021
17

Proximity proteomics of C9orf72 dipeptide repeat proteins identifies molecular chaperones as modifiers of poly-GA aggregation.
Feilin Liu, Dmytro Morderer, Melissa C Wren, Sara A Vettleson-Trutza, Yanzhe Wang, Benjamin E Rabichow, Michelle R Salemi, Brett S Phinney, Björn Oskarsson, Dennis W Dickson,[...]. Acta Neuropathol Commun 2022
0

The progress in C9orf72 research: ALS/FTD pathogenesis, functions and structure.
Lan Jiang, Tizhong Zhang, Kefeng Lu, Shiqian Qi. Small GTPases 2021
2


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