J L Cabrera, F de Freitas, D K Satpaev, V Z Slepak. Biochem Biophys Res Commun 1998
Times Cited: 118
Times Cited: 118
B E Snow, A M Krumins, G M Brothers, S F Lee, M A Wall, S Chung, J Mangion, S Arya, A G Gilman, D P Siderovski. Proc Natl Acad Sci U S A 1998
Times Cited: 226
Times Cited: 226
Times cited
Targeting G protein-coupled receptor signalling by blocking G proteins.
Adrian P Campbell, Alan V Smrcka. Nat Rev Drug Discov 2018
Adrian P Campbell, Alan V Smrcka. Nat Rev Drug Discov 2018
Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by Gαo and R7-binding Protein.
Junior Tayou, Qiang Wang, Geeng-Fu Jang, Alexey N Pronin, Cesare Orlandi, Kirill A Martemyanov, John W Crabb, Vladlen Z Slepak. J Biol Chem 2016
Junior Tayou, Qiang Wang, Geeng-Fu Jang, Alexey N Pronin, Cesare Orlandi, Kirill A Martemyanov, John W Crabb, Vladlen Z Slepak. J Biol Chem 2016
Intermolecular Interaction between Anchoring Subunits Specify Subcellular Targeting and Function of RGS Proteins in Retina ON-Bipolar Neurons.
Ignacio Sarria, Cesare Orlandi, Maureen A McCall, Ronald G Gregg, Kirill A Martemyanov. J Neurosci 2016
Ignacio Sarria, Cesare Orlandi, Maureen A McCall, Ronald G Gregg, Kirill A Martemyanov. J Neurosci 2016
Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain.
Cesare Orlandi, Keqiang Xie, Ikuo Masuho, Ana Fajardo-Serrano, Rafael Lujan, Kirill A Martemyanov. J Biol Chem 2015
Cesare Orlandi, Keqiang Xie, Ikuo Masuho, Ana Fajardo-Serrano, Rafael Lujan, Kirill A Martemyanov. J Biol Chem 2015
Differential effects of the Gβ5-RGS7 complex on muscarinic M3 receptor-induced Ca2+ influx and release.
Darla Karpinsky-Semper, Claude-Henry Volmar, Shaun P Brothers, Vladlen Z Slepak. Mol Pharmacol 2014
Darla Karpinsky-Semper, Claude-Henry Volmar, Shaun P Brothers, Vladlen Z Slepak. Mol Pharmacol 2014
Decreased RGS6 expression is associated with poor prognosis in pancreatic cancer patients.
Nan Jiang, Ruihua Xue, Fangfang Bu, Xin Tong, Jiankun Qiang, Rong Liu. Int J Clin Exp Pathol 2014
Nan Jiang, Ruihua Xue, Fangfang Bu, Xin Tong, Jiankun Qiang, Rong Liu. Int J Clin Exp Pathol 2014
Macromolecular composition dictates receptor and G protein selectivity of regulator of G protein signaling (RGS) 7 and 9-2 protein complexes in living cells.
Ikuo Masuho, Keqiang Xie, Kirill A Martemyanov. J Biol Chem 2013
Ikuo Masuho, Keqiang Xie, Kirill A Martemyanov. J Biol Chem 2013
Timing is everything: GTPase regulation in phototransduction.
Vadim Y Arshavsky, Theodore G Wensel. Invest Ophthalmol Vis Sci 2013
Vadim Y Arshavsky, Theodore G Wensel. Invest Ophthalmol Vis Sci 2013
Subcellular localization of regulator of G protein signaling RGS7 complex in neurons and transfected cells.
Evangelos Liapis, Simone Sandiford, Qiang Wang, Gabriel Gaidosh, Dario Motti, Konstantin Levay, Vladlen Z Slepak. J Neurochem 2012
Evangelos Liapis, Simone Sandiford, Qiang Wang, Gabriel Gaidosh, Dario Motti, Konstantin Levay, Vladlen Z Slepak. J Neurochem 2012
Regulator of G protein signaling 6 (RGS6) induces apoptosis via a mitochondrial-dependent pathway not involving its GTPase-activating protein activity.
Biswanath Maity, Jianqi Yang, Jie Huang, Ryan W Askeland, Soumen Bera, Rory A Fisher. J Biol Chem 2011
Biswanath Maity, Jianqi Yang, Jie Huang, Ryan W Askeland, Soumen Bera, Rory A Fisher. J Biol Chem 2011
Gi/o signaling and the palmitoyltransferase DHHC2 regulate palmitate cycling and shuttling of RGS7 family-binding protein.
Lixia Jia, Maurine E Linder, Kendall J Blumer. J Biol Chem 2011
Lixia Jia, Maurine E Linder, Kendall J Blumer. J Biol Chem 2011
Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets.
Adam J Kimple, Dustin E Bosch, Patrick M Giguère, David P Siderovski. Pharmacol Rev 2011
Adam J Kimple, Dustin E Bosch, Patrick M Giguère, David P Siderovski. Pharmacol Rev 2011
Knockout of G protein β5 impairs brain development and causes multiple neurologic abnormalities in mice.
Jian-Hua Zhang, Mritunjay Pandey, Erica M Seigneur, Leelamma M Panicker, Lily Koo, Owen M Schwartz, Weiping Chen, Ching-Kang Chen, William F Simonds. J Neurochem 2011
Jian-Hua Zhang, Mritunjay Pandey, Erica M Seigneur, Leelamma M Panicker, Lily Koo, Owen M Schwartz, Weiping Chen, Ching-Kang Chen, William F Simonds. J Neurochem 2011
Molecular organization of the complex between the muscarinic M3 receptor and the regulator of G protein signaling, Gbeta(5)-RGS7.
Simone L Sandiford, Qiang Wang, Konstantin Levay, Peter Buchwald, Vladlen Z Slepak. Biochemistry 2010
Simone L Sandiford, Qiang Wang, Konstantin Levay, Peter Buchwald, Vladlen Z Slepak. Biochemistry 2010
The Gbeta5-RGS7 complex selectively inhibits muscarinic M3 receptor signaling via the interaction between the third intracellular loop of the receptor and the DEP domain of RGS7.
Simone L Sandiford, Vladlen Z Slepak. Biochemistry 2009
Simone L Sandiford, Vladlen Z Slepak. Biochemistry 2009
The R7 RGS protein family: multi-subunit regulators of neuronal G protein signaling.
Garret R Anderson, Ekaterina Posokhova, Kirill A Martemyanov. Cell Biochem Biophys 2009
Garret R Anderson, Ekaterina Posokhova, Kirill A Martemyanov. Cell Biochem Biophys 2009
Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons.
Yan Cao, Ikuo Masuho, Haruhisa Okawa, Keqiang Xie, Junko Asami, Paul J Kammermeier, Dennis M Maddox, Takahisa Furukawa, Takayoshi Inoue, Alapakkam P Sampath,[...]. J Neurosci 2009
Yan Cao, Ikuo Masuho, Haruhisa Okawa, Keqiang Xie, Junko Asami, Paul J Kammermeier, Dennis M Maddox, Takahisa Furukawa, Takayoshi Inoue, Alapakkam P Sampath,[...]. J Neurosci 2009
Regulators of G protein signaling proteins as central components of G protein-coupled receptor signaling complexes.
Kelly L McCoy, John R Hepler. Prog Mol Biol Transl Sci 2009
Kelly L McCoy, John R Hepler. Prog Mol Biol Transl Sci 2009
Nuclear trafficking of regulator of G protein signaling proteins and their roles in the nucleus.
Jie Huang, Rory A Fisher. Prog Mol Biol Transl Sci 2009
Jie Huang, Rory A Fisher. Prog Mol Biol Transl Sci 2009
Structure, function, and localization of Gβ5-RGS complexes.
Vladlen Z Slepak. Prog Mol Biol Transl Sci 2009
Vladlen Z Slepak. Prog Mol Biol Transl Sci 2009
Biology and functions of the RGS9 isoforms.
Kirill A Martemyanov, Vadim Y Arshavsky. Prog Mol Biol Transl Sci 2009
Kirill A Martemyanov, Vadim Y Arshavsky. Prog Mol Biol Transl Sci 2009
Postnatal induction and localization of R7BP, a membrane-anchoring protein for regulator of G protein signaling 7 family-Gbeta5 complexes in brain.
D Grabowska, M Jayaraman, K M Kaltenbronn, S L Sandiford, Q Wang, S Jenkins, V Z Slepak, Y Smith, K J Blumer. Neuroscience 2008
D Grabowska, M Jayaraman, K M Kaltenbronn, S L Sandiford, Q Wang, S Jenkins, V Z Slepak, Y Smith, K J Blumer. Neuroscience 2008
G protein βγ subunits: central mediators of G protein-coupled receptor signaling.
A V Smrcka. Cell Mol Life Sci 2008
A V Smrcka. Cell Mol Life Sci 2008
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina.
Joseph H Song, Hongman Song, Theodore G Wensel, Maxim Sokolov, Kirill A Martemyanov. Mol Cell Neurosci 2007
Joseph H Song, Hongman Song, Theodore G Wensel, Maxim Sokolov, Kirill A Martemyanov. Mol Cell Neurosci 2007
Intramolecular interaction between the DEP domain of RGS7 and the Gbeta5 subunit.
Vijaya Narayanan, Simone L Sandiford, Qiang Wang, Tal Keren-Raifman, Konstantin Levay, Vladlen Z Slepak. Biochemistry 2007
Vijaya Narayanan, Simone L Sandiford, Qiang Wang, Tal Keren-Raifman, Konstantin Levay, Vladlen Z Slepak. Biochemistry 2007
R7-binding protein targets the G protein beta 5/R7-regulator of G protein signaling complex to lipid rafts in neuronal cells and brain.
Lylia Nini, Abdul A Waheed, Leelamma M Panicker, Meggan Czapiga, Jian-Hua Zhang, William F Simonds. BMC Biochem 2007
Lylia Nini, Abdul A Waheed, Leelamma M Panicker, Meggan Czapiga, Jian-Hua Zhang, William F Simonds. BMC Biochem 2007
Accessory proteins for G proteins: partners in signaling.
Motohiko Sato, Joe B Blumer, Violaine Simon, Stephen M Lanier. Annu Rev Pharmacol Toxicol 2006
Motohiko Sato, Joe B Blumer, Violaine Simon, Stephen M Lanier. Annu Rev Pharmacol Toxicol 2006
Structural basis of function in heterotrimeric G proteins.
William M Oldham, Heidi E Hamm. Q Rev Biophys 2006
William M Oldham, Heidi E Hamm. Q Rev Biophys 2006
R7BP, a novel neuronal protein interacting with RGS proteins of the R7 family.
Kirill A Martemyanov, Peter J Yoo, Nikolai P Skiba, Vadim Y Arshavsky. J Biol Chem 2005
Kirill A Martemyanov, Peter J Yoo, Nikolai P Skiba, Vadim Y Arshavsky. J Biol Chem 2005
R7BP: a surprising new link between G proteins, RGS proteins, and nuclear signaling in the brain.
John R Hepler. Sci STKE 2005
John R Hepler. Sci STKE 2005
The G betagamma dimer as a novel source of selectivity in G-protein signaling: GGL-ing at convention.
Miller B Jones, David P Siderovski, Shelley B Hooks. Mol Interv 2004
Miller B Jones, David P Siderovski, Shelley B Hooks. Mol Interv 2004
Enhancement of pheromone response by RGS9 and Gbeta5 in yeast.
Seena K Ajit, Kathleen H Young. Biochem Biophys Res Commun 2004
Seena K Ajit, Kathleen H Young. Biochem Biophys Res Commun 2004
Analysis of the regulation of microtubule dynamics by interaction of RGSZ1 (RGS20) with the neuronal stathmin, SCG10.
Andrew B Nixon, Patrick J Casey. Methods Enzymol 2004
Andrew B Nixon, Patrick J Casey. Methods Enzymol 2004
Biochemical purification and functional analysis of complexes between the G-protein subunit Gbeta5 and RGS proteins.
D Scott Witherow, Vladlen Z Slepak. Methods Enzymol 2004
D Scott Witherow, Vladlen Z Slepak. Methods Enzymol 2004
Assays of nuclear localization of R7/Gbeta5 complexes.
William F Simonds, Geoffrey E Woodard, Jian-Hua Zhang. Methods Enzymol 2004
William F Simonds, Geoffrey E Woodard, Jian-Hua Zhang. Methods Enzymol 2004
RGS6, RGS7, RGS9, and RGS11 stimulate GTPase activity of Gi family G-proteins with differential selectivity and maximal activity.
Shelley B Hooks, Gary L Waldo, James Corbitt, Erik T Bodor, Andrejs M Krumins, T Kendall Harden. J Biol Chem 2003
Shelley B Hooks, Gary L Waldo, James Corbitt, Erik T Bodor, Andrejs M Krumins, T Kendall Harden. J Biol Chem 2003
Ggamma subunit-selective G protein beta 5 mutant defines regulators of G protein signaling protein binding requirement for nuclear localization.
Alexandra M Rojkova, Geoffrey E Woodard, Tzu-Chuan Huang, Christian A Combs, Jian-Hua Zhang, William F Simonds. J Biol Chem 2003
Alexandra M Rojkova, Geoffrey E Woodard, Tzu-Chuan Huang, Christian A Combs, Jian-Hua Zhang, William F Simonds. J Biol Chem 2003
Regulators of G-protein signalling: multifunctional proteins with impact on signalling in the cardiovascular system.
Thomas Wieland, Clemens Mittmann. Pharmacol Ther 2003
Thomas Wieland, Clemens Mittmann. Pharmacol Ther 2003
Direct interactions between the heterotrimeric G protein subunit G beta 5 and the G protein gamma subunit-like domain-containing regulator of G protein signaling 11: gain of function of cyan fluorescent protein-tagged G gamma 3.
Janice Y Zhou, Peter T Toth, Richard J Miller. J Pharmacol Exp Ther 2003
Janice Y Zhou, Peter T Toth, Richard J Miller. J Pharmacol Exp Ther 2003
Snapin interacts with the N-terminus of regulator of G protein signaling 7.
Rachel A Hunt, Wade Edris, Pranab K Chanda, Bart Nieuwenhuijsen, Kathleen H Young. Biochem Biophys Res Commun 2003
Rachel A Hunt, Wade Edris, Pranab K Chanda, Bart Nieuwenhuijsen, Kathleen H Young. Biochem Biophys Res Commun 2003
G beta 5.RGS7 inhibits G alpha q-mediated signaling via a direct protein-protein interaction.
D Scott Witherow, Steven C Tovey, Qiang Wang, Gary B Willars, Vladlen Z Slepak. J Biol Chem 2003
D Scott Witherow, Steven C Tovey, Qiang Wang, Gary B Willars, Vladlen Z Slepak. J Biol Chem 2003
Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5.
Ching-Kang Chen, Pamela Eversole-Cire, Haikun Zhang, Valeria Mancino, Yu-Jiun Chen, Wei He, Theodore G Wensel, Melvin I Simon. Proc Natl Acad Sci U S A 2003
Ching-Kang Chen, Pamela Eversole-Cire, Haikun Zhang, Valeria Mancino, Yu-Jiun Chen, Wei He, Theodore G Wensel, Melvin I Simon. Proc Natl Acad Sci U S A 2003
Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants.
Tapan K Chatterjee, Zhengyu Liu, Rory A Fisher. J Biol Chem 2003
Tapan K Chatterjee, Zhengyu Liu, Rory A Fisher. J Biol Chem 2003
A novel kind of G protein heterodimer: the G beta5-RGS complex.
D Scott Witherow, Vladlen Z Slepak. Recept Channels 2003
D Scott Witherow, Vladlen Z Slepak. Recept Channels 2003
Insights into G protein structure, function, and regulation.
Theresa M Cabrera-Vera, Jurgen Vanhauwe, Tarita O Thomas, Martina Medkova, Anita Preininger, Maria R Mazzoni, Heidi E Hamm. Endocr Rev 2003
Theresa M Cabrera-Vera, Jurgen Vanhauwe, Tarita O Thomas, Martina Medkova, Anita Preininger, Maria R Mazzoni, Heidi E Hamm. Endocr Rev 2003
G proteins and phototransduction.
Vadim Y Arshavsky, Trevor D Lamb, Edward N Pugh. Annu Rev Physiol 2002
Vadim Y Arshavsky, Trevor D Lamb, Edward N Pugh. Annu Rev Physiol 2002
The interaction of RGSZ1 with SCG10 attenuates the ability of SCG10 to promote microtubule disassembly.
Andrew B Nixon, Gabriele Grenningloh, Patrick J Casey. J Biol Chem 2002
Andrew B Nixon, Gabriele Grenningloh, Patrick J Casey. J Biol Chem 2002
Spinal cord injury induces expression of RGS7 in microglia/macrophages in rats.
Oliver N Hausmann, Wen-Hui Hu, Tal Keren-Raifman, D Scott Witherow, Qiang Wang, Konstantin Levay, Beata Frydel, Vladlen Z Slepak, John R Bethea. Eur J Neurosci 2002
Oliver N Hausmann, Wen-Hui Hu, Tal Keren-Raifman, D Scott Witherow, Qiang Wang, Konstantin Levay, Beata Frydel, Vladlen Z Slepak, John R Bethea. Eur J Neurosci 2002