M C Naski, J S Colvin, J D Coffin, D M Ornitz. Development 1998
Times Cited: 303
Times Cited: 303
David M Ornitz, Pierre J Marie. Genes Dev 2015
Times Cited: 217
Times Cited: 217
List of shared articles
Times cited
Excessive osteoclast activation by osteoblast paracrine factor RANKL is a major cause of the abnormal long bone phenotype in Apert syndrome model mice.
Hye-Rim Shin, Bong-Soo Kim, Hyun-Jung Kim, Heein Yoon, Woo-Jin Kim, Je-Yong Choi, Hyun-Mo Ryoo. J Cell Physiol 2022
Hye-Rim Shin, Bong-Soo Kim, Hyun-Jung Kim, Heein Yoon, Woo-Jin Kim, Je-Yong Choi, Hyun-Mo Ryoo. J Cell Physiol 2022
New developments in the biology of fibroblast growth factors.
David M Ornitz, Nobuyuki Itoh. WIREs Mech Dis 2022
David M Ornitz, Nobuyuki Itoh. WIREs Mech Dis 2022
Oncogenic FGFR Fusions Produce Centrosome and Cilia Defects by Ectopic Signaling.
Alexandru Nita, Sara P Abraham, Pavel Krejci, Michaela Bosakova. Cells 2021
Alexandru Nita, Sara P Abraham, Pavel Krejci, Michaela Bosakova. Cells 2021
Longitudinal Imaging of the Skull Base Synchondroses Demonstrate Prevention of a Premature Ossification After Recifercept Treatment in Mouse Model of Achondroplasia.
Guylene Rignol, Stephanie Garcia, Florence Authier, Kaamula Smith, Lionel Tosello, Raphael Marsault, Pierre Dellugat, Diogo Goncalves, Marlene Brouillard, Jeffrey Stavenhagen,[...]. JBMR Plus 2021
Guylene Rignol, Stephanie Garcia, Florence Authier, Kaamula Smith, Lionel Tosello, Raphael Marsault, Pierre Dellugat, Diogo Goncalves, Marlene Brouillard, Jeffrey Stavenhagen,[...]. JBMR Plus 2021
In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia.
Diogo Gonçalves, Guylène Rignol, Pierre Dellugat, Guido Hartmann, Stephanie Sarrazy Garcia, Jeffrey Stavenhagen, Luca Santarelli, Elvire Gouze, Christian Czech. PLoS One 2020
Diogo Gonçalves, Guylène Rignol, Pierre Dellugat, Guido Hartmann, Stephanie Sarrazy Garcia, Jeffrey Stavenhagen, Luca Santarelli, Elvire Gouze, Christian Czech. PLoS One 2020
Fibroblast growth factors in skeletal development.
David M Ornitz, Pierre J Marie. Curr Top Dev Biol 2019
David M Ornitz, Pierre J Marie. Curr Top Dev Biol 2019
Activated FGFR3 prevents subchondral bone sclerosis during the development of osteoarthritis in transgenic mice with achondroplasia.
Toshiaki Okura, Masaki Matsushita, Kenichi Mishima, Ryusaku Esaki, Taisuke Seki, Naoki Ishiguro, Hiroshi Kitoh. J Orthop Res 2018
Toshiaki Okura, Masaki Matsushita, Kenichi Mishima, Ryusaku Esaki, Taisuke Seki, Naoki Ishiguro, Hiroshi Kitoh. J Orthop Res 2018
Time-dependent contribution of BMP, FGF, IGF, and HH signaling to the proliferation of mesenchymal stroma cells during chondrogenesis.
Jennifer Fischer, Natalie Knoch, Tanja Sims, Nils Rosshirt, Wiltrud Richter. J Cell Physiol 2018
Jennifer Fischer, Natalie Knoch, Tanja Sims, Nils Rosshirt, Wiltrud Richter. J Cell Physiol 2018
Fibroblast Growth Factor 2 and Its Receptors in Bone Biology and Disease.
J Douglas Coffin, Collin Homer-Bouthiette, Marja Marie Hurley. J Endocr Soc 2018
J Douglas Coffin, Collin Homer-Bouthiette, Marja Marie Hurley. J Endocr Soc 2018
C-type natriuretic peptide analog treatment of craniosynostosis in a Crouzon syndrome mouse model.
Greg Holmes, Lening Zhang, Joshua Rivera, Ryan Murphy, Claudia Assouline, Lorraine Sullivan, Todd Oppeneer, Ethylin Wang Jabs. PLoS One 2018
Greg Holmes, Lening Zhang, Joshua Rivera, Ryan Murphy, Claudia Assouline, Lorraine Sullivan, Todd Oppeneer, Ethylin Wang Jabs. PLoS One 2018
Achondroplasia: Development, pathogenesis, and therapy.
David M Ornitz, Laurence Legeai-Mallet. Dev Dyn 2017
David M Ornitz, Laurence Legeai-Mallet. Dev Dyn 2017
Clinical dosage of meclozine promotes longitudinal bone growth, bone volume, and trabecular bone quality in transgenic mice with achondroplasia.
Masaki Matsushita, Ryusaku Esaki, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno, Hiroshi Kitoh. Sci Rep 2017
Masaki Matsushita, Ryusaku Esaki, Kenichi Mishima, Naoki Ishiguro, Kinji Ohno, Hiroshi Kitoh. Sci Rep 2017
ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3.
Lukas Balek, Iva Gudernova, Iva Vesela, Marek Hampl, Veronika Oralova, Michaela Kunova Bosakova, Miroslav Varecha, Pavel Nemec, Terence Hall, Giovanni Abbadessa,[...]. Bone 2017
Lukas Balek, Iva Gudernova, Iva Vesela, Marek Hampl, Veronika Oralova, Michaela Kunova Bosakova, Miroslav Varecha, Pavel Nemec, Terence Hall, Giovanni Abbadessa,[...]. Bone 2017
Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor.
Leia C Shuhaibar, Jerid W Robinson, Giulia Vigone, Ninna P Shuhaibar, Jeremy R Egbert, Valentina Baena, Tracy F Uliasz, Deborah Kaback, Siu-Pok Yee, Robert Feil,[...]. Elife 2017
Leia C Shuhaibar, Jerid W Robinson, Giulia Vigone, Ninna P Shuhaibar, Jeremy R Egbert, Valentina Baena, Tracy F Uliasz, Deborah Kaback, Siu-Pok Yee, Robert Feil,[...]. Elife 2017
A combined series of Fgf9 and Fgf18 mutant alleles identifies unique and redundant roles in skeletal development.
Irene H Hung, Gary C Schoenwolf, Mark Lewandoski, David M Ornitz. Dev Biol 2016
Irene H Hung, Gary C Schoenwolf, Mark Lewandoski, David M Ornitz. Dev Biol 2016
The cartilage extracellular matrix as a transient developmental scaffold for growth plate maturation.
James Melrose, Cindy Shu, John M Whitelock, Megan S Lord. Matrix Biol 2016
James Melrose, Cindy Shu, John M Whitelock, Megan S Lord. Matrix Biol 2016
Genetic insights into the mechanisms of Fgf signaling.
J Richard Brewer, Pierre Mazot, Philippe Soriano. Genes Dev 2016
J Richard Brewer, Pierre Mazot, Philippe Soriano. Genes Dev 2016
FGF signaling in the osteoprogenitor lineage non-autonomously regulates postnatal chondrocyte proliferation and skeletal growth.
Kannan Karuppaiah, Kai Yu, Joohyun Lim, Jianquan Chen, Craig Smith, Fanxin Long, David M Ornitz. Development 2016
Kannan Karuppaiah, Kai Yu, Joohyun Lim, Jianquan Chen, Craig Smith, Fanxin Long, David M Ornitz. Development 2016
Tyrosine kinase inhibitor NVP-BGJ398 functionally improves FGFR3-related dwarfism in mouse model.
Davide Komla-Ebri, Emilie Dambroise, Ina Kramer, Catherine Benoist-Lasselin, Nabil Kaci, Cindy Le Gall, Ludovic Martin, Patricia Busca, Florent Barbault, Diana Graus-Porta,[...]. J Clin Invest 2016
Davide Komla-Ebri, Emilie Dambroise, Ina Kramer, Catherine Benoist-Lasselin, Nabil Kaci, Cindy Le Gall, Ludovic Martin, Patricia Busca, Florent Barbault, Diana Graus-Porta,[...]. J Clin Invest 2016